Archer FusionPlex Oncology Research

The Archer® FusionPlex® Oncology Research Kit is a targeted next generation sequencing NGS assay to simultaneously detect and identify fusions and other mutations associated with 74 genes found in RNA transcripts that are linked to various cancers, This kit is extensive and purpose-built to advance fusion discovery, including research efforts in the area of Ph-like ALL fusions, Studies are

Archer™ FusionPlex™ Sarcoma Panel

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The Archer™ FusionPlex™ Sarcoma Panel is a target-enrichment assay for rapid detection and identification of translocations of genes associated with sarcoma, Libraries are created by using the FusionPlex assay in conjunction with the Archer™ Universal RNA Fusion Detection Kits AK0024-8, AK0025-8 and Archer™ MBC Adapters for Illumina® or Ion Torrent™, Once sequenced, Archer

Archer FusionPlex NGS Assays and Bioinformatic Analysis

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Archer FusionPlex NGS assays show sensitive detection of translocations and point mutations, In the figure at left, TPM3:NTRK1 fusion-containing RNA was serially diluted into fusion-negative background RNA and libraries were prepared using the Archer FusionPlex CTL Assay using 100ng total input, After sequencing, fusions were called based on sequencing reads spanning the fusion breakpoint down

Archer FusionPlex Heme v2 Kit

The Archer FusionPlex Heme v2 Kit is an RNA-based targeted sequencing assay that detects and identifies fusions of 87 genes associated with hematological malignancies, Using Archer’s proprietary Anchored Multiplex PCR-based enrichment AMP TM, fusions of all genes in this kit can be identified in a single sequencing assay, even without prior knowledge of fusion partners or breakpoints

Archer FusionPlex Protocol for Illumina

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Archer® FusionPlex® Protocol for Illumina® Protocol ®Archer® ®FusionPlex Protocol for Illumina LA135,1 3 www,archerdx,com In This Guide This protocol is a guide to using Archer NGS library preparation kits, MBC adapters and gene enrichment panels for targeted sequencing of

Archer™ Assay Designer

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The Archer FusionPlex™ and VariantPlex™ target-enrichment assays are used to create libraries for next generation sequencing, Libraries are created by using the FusionPlex assay in conjunction with the Archer Universal RNA Reagent Kits V2 AK0040-8, AK0042-8, or VariantPlex assay in conjunction with the Archer Universal DNA Reagent Kit V2 for Illumina® AK0037-8 and Archer™ MBC

Comprehensive Genomic Profiling

We offer a suite of research products that are powered by proprietary Anchored Multiplex PCR AMP™ chemistry, including FusionPlex ®, VariantPlex ®, LiquidPlex™ and Immunoverse™, Additionally, we are developing IVD products for solid tumor biomarker identification and Personalized Cancer Monitoring PCM™ but which are not yet approved for clinical or diagnostic use,

FusionPlex® Lung v2

The FusionPlex® Lung v2 panel is a targeted Next-Generation Sequencing NGS research product that expands on the well-adopted FusionPlex® Lung panel to further drive discovery,The updated design covers newly published fusion breakpoints and isoforms of interest in key gene targets including the NTRKs and aligns with existing guidelines for non-small cell lung cancer research, including

FusionPlex® Pan Solid Tumor v2

The FusionPlex® Pan Solid Tumor v2 panel is a targeted next-generation sequencing NGS research product that expands on the FusionPlex Solid Tumor panel to include key fusions and variants relevant across solid tumors and sarcomas in 137 genes, Representing our most comprehensive fusion coverage, the updated design includes key fusions and variants, FusionPlex® uses RNA instead of DNA as

FusionPlex® Solid Tumor Panel

The FusionPlex® Solid Tumor Panel is based on next generation sequencing of RNA cDNA from solid tumor tissue to detect somatic oncogenic gene fusions involving any of over 100 genes associated with solid tumors, without prior knowledge of the fusion partners or the breakpoints of the translocations, This test can also be ordered for a single

Archer FusionPlex Acute Lymphoblastic Leukemia ALL

The Archer® FusionPlex® Acute Lymphoblastic Leukemia ALL Kit is a targeted next-generation sequencing assay to detect and identify fusions, point mutations and expression levels in 81 genes associated with Acute Lymphoblastic Leukemia, including recurrent Ph-Like ALL fusion events, The kit uses Archer’s proprietary Anchored Multiplex PCR AMP™-based enrichment to detect fusions, even

Archer DX

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Comparison of four next generation sequencing platforms

For fusion with unknown partners, FusionPlex identified the largest number of ETV1 fusions because it had the highest exon coverage for ETV1, Among these, SNRPN-ETV1 and MALAT1-ETV1, were novel findings, To determine reportability of low-level calls of highly prevalent fusions, such as TMPRSS2-ERG, we propose the use of percent fusion reads over total number of reads per sample instead of the

Intraarticular Inflammatory Myofibroblastic Tumor of the

Intraarticular Inflammatory Myofibroblastic Tumor of the Left Knee With ALK-CARS Fusion Detected With Archer Fusionplex Sarcoma NGS Panel: Case Report and Literature Review Int J Surg Pathol, 2020 Jul 7;1066896920937770, doi: 10,1177/1066896920937770, Online ahead of print, Authors