Microbiome and Autoimmune Uveitis

Autoimmune or non-infectious uveitis is a sight-threatening intraocular inflammation that affects the neuroretina, It is strongly T cell driven, but the precise causative mechanisms are not fully understood, We and others observed that depletion of gut microbiota in animal models of uveitis attenuated disease, Using a spontaneous model of the disease, we questioned how retina-specific

In uveitis, bacteria in gut may instruct immune cells to

Autoimmune uveitis accounts for more than 10 percent of severe visual disability in the United States, Corticosteroids provide a blanket approach to the disorder by quelling inflammation, but their long-term use can lead to adverse side effects, Understanding what spurs autoimmune uveitis is fundamental to the development of safer long-term therapies and possibly even strategies for preventing

Uveitis

Overview

Uveitis and autoimmune hepatitis, a real entity? A case

Thus, it is indeed presented as autoimmune uveitis presumably associated with AIH, Moreover, the patient’s biomarkers were suggestive of competent immunity, Lim et al, have described the pattern of uveitis that is linked to AIH as a chronic, bilateral, and persistent uveitis with sight-threatening complications, Uveitis associated with AIH can present suddenly as anterior uveitis or

Uveitis

Autoimmune conditions known to cause uveitis include: ankylosing spondylitis – a condition where the spine and other areas of the body become inflamed, reactive arthritis – a condition that causes inflammation in various areas of the body, conditions that cause bowel inflammation – such as Crohn’s disease and ulcerative colitis,

Rodent Models of Experimental Autoimmune Uveitis

The model of experimental autoimmune uveitis EAU in mice and in rats is described, EAU targets immunologically privileged retinal antigens and serves as a model of autoimmune uveitis in humans as well as a model for autoimmunity in a more general sense, EAU is a well-characterized, robust, and reproducible model that is easily followed and quantitated, It is inducible with synthetic peptides

Eyes

Uveitis is inflammation of the middle layer of tissue in the eye, which extends from the iris at the front of the eye to the retina and choroid at the back of the eye, Iritis is a type of uveitis, It is inflammation of the iris, the coloured part of the eye, It is more correctly called anterior uveitis, The cause is unknown in about 40 per cent of cases, but may include infections, autoimmune

Frontiers

As one of the leading causes of blindness worldwide, uveitis is an important disease, The exact pathogenesis of autoimmune uveitis is not entirely elucidated to date, Equine recurrent uveitis ERU represents the only spontaneous animal model for autoimmune uveitis in humans, As the metabolism of immune cells is an emerging field in research and gains more and more significance to take part in

How to Tell If Uveitis Is a Sign of Something More Serious

Autoimmune Diseases, These happen when your immune system attacks your organs and tissues, It can affect your eyes, too, Most cases of uveitis are caused …

Paediatric autoimmune and autoinflammatory conditions

Childhood uveitis comprises a collection of heterogenous ocular phenotypes which are associated with a diverse range of childhood autoimmune and autoinflammatory disorders, Of these genetic and/or acquired disorders, juvenile idiopathic arthritis is the most common, affecting 30-80% of children with uveitis, Up to a third of children with uveitis have ‘isolated’ idiopathic disease and do not

Uveitis – National Eye Institute

Uveitis is a general term describing a group of diseases that produce swelling and destroy eye tissues, These diseases can cause minor or severe vision loss, Learn more about uveitis, including its causes, symptoms, diagnosis, and treatment and research,

Uveitis

Overview

Cureus

The right environmental trigger can lead to immune system activation, which, in turn, can create an autoimmune reaction, Although each autoimmune disease is characterized by specific symptoms, many nonspecific symptoms can make these conditions difficult to diagnose, In this literature review, we seek an association between immunization-induced uveitis and an autoimmune …